Description
Product Characteristics:
May play a role in targeting PRKCA to caveolae.
Subcellular location: Cytoplasm
Synonyms: SDR, CAVIN2, PS-p68, cavin-2, Serum deprivation-response protein, Phosphatidylserine-binding protein, SDPR
Target Information: This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]